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    <link:loc xlink:href="jazz-20190630.xsd#jazz_IncreaseDecreaseInOperatingLeaseAssets" xlink:label="loc_jazz_IncreaseDecreaseInOperatingLeaseAssets_54F979E6550F420895D96749D0D4F3B4" xlink:type="locator" />
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_E1D68B1D4CA23F03201A6749D0D59B2B" xlink:type="locator" />
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    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_2EE592CEA01C0D0413AE6749D0D6B6BF_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_2EE592CEA01C0D0413AE6749D0D6B6BF" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Net Cash Provided by (Used in) Investing Activities [Abstract]</link:label>
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    <link:label id="lab_us-gaap_ProceedsFromSaleMaturityAndCollectionsOfInvestments_C4C6F32C51BF73DC66FE6749D0D6FFC2_terseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromSaleMaturityAndCollectionsOfInvestments_C4C6F32C51BF73DC66FE6749D0D6FFC2" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Proceeds from maturity of investments</link:label>
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    <link:label id="lab_jazz_PaymentstoAcquireInProcessResearchandDevelopmentOtherThanThroughBusinessCombination_B88B8482100163919FD26749D0D62112_negatedLabel_en-US" xlink:label="lab_jazz_PaymentstoAcquireInProcessResearchandDevelopmentOtherThanThroughBusinessCombination_B88B8482100163919FD26749D0D62112" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Acquired in-process research and development</link:label>
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    <link:label id="lab_us-gaap_PaymentsToAcquireProductiveAssets_64BB1710BE2056A38A896749D0D6BEC5_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsToAcquireProductiveAssets_64BB1710BE2056A38A896749D0D6BEC5" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Purchases of property, plant and equipment</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsToAcquireInvestments" xlink:label="loc_us-gaap_PaymentsToAcquireInvestments_9466A07BA9E9D0134AA86749D0D78E35" xlink:type="locator" />
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    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities_52D16F9CC66FC56DD5E76749D0D7B0DF_totalLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities_52D16F9CC66FC56DD5E76749D0D7B0DF" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Net cash provided by (used in) investing activities</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities_52D16F9CC66FC56DD5E76749D0D7B0DF_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInInvestingActivities_52D16F9CC66FC56DD5E76749D0D7B0DF" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Net Cash Provided by (Used in) Investing Activities</link:label>
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    <link:label id="lab_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions_3B141651DEAA0A74925A6749D0D7015B_terseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions_3B141651DEAA0A74925A6749D0D7015B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Proceeds from employee equity incentive and purchase plans</link:label>
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    <link:label id="lab_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_FF1805B696EAEB1F8FAB6749D0D849C1_negatedLabel_en-US" xlink:label="lab_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_FF1805B696EAEB1F8FAB6749D0D849C1" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Payment of employee withholding taxes related to share-based awards</link:label>
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    <link:label id="lab_us-gaap_RepaymentsOfSecuredDebt_5A4E23346ADCC328AFC36749D0D81EF3_negatedLabel_en-US" xlink:label="lab_us-gaap_RepaymentsOfSecuredDebt_5A4E23346ADCC328AFC36749D0D81EF3" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Repayments of long-term debt</link:label>
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    <link:label id="lab_jazz_PaymentsForProceedsFromTenantAllowanceFinancingActivities_9775715F109267C3D8AB6749D0D891D1_negatedLabel_en-US" xlink:label="lab_jazz_PaymentsForProceedsFromTenantAllowanceFinancingActivities_9775715F109267C3D8AB6749D0D891D1" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Proceeds from tenant improvement allowance on build-to-suit lease</link:label>
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